The Second Edition of this text maintains its reputation as a comprehensive clinical reference for neurologists and geneticists treating patients with genetic neurologic diseases. The remarkable achievements made in the fields of molecular and cellular neurobiology and molecular neurogenetics have been applied to genetic neurological disease with equally dramatic results. The molecular pathogenesis of neurological disease is a recent development, and it is fair to say that most of the scientific material presented in the Second Edition was not available even five years ago. This surge of molecular data of neurological disease is a strong testimony to the vitality of investigators in the field.
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